Science for Youthful-Looking Skin.
Kappa-Elastine is a unique, patented molecule developed through scientific research and at the heart of Laboratoire Vivaligne’s expertise and KDerm skincare products. Its action is based on a mechanism essential to maintaining youthful-looking skin: the preservation and renewal of collagen and elastin.
Thanks to its unique properties, Kappa-Elastine helps improve skin firmness and elasticity while reducing the visible signs of skin aging.
Elastin, Essential to Skin Structure
Naturally present in the dermis, elastin is an essential component of the skin’s structure. It plays a fundamental role in maintaining skin suppleness and elasticity.
Together with collagen, it forms a supportive network known as the Extracellular Matrix (ECM), which is essential for maintaining skin structure and firmness. From the age of 25, elastin production begins to decline, weakening this network. The skin gradually loses its firmness and suppleness, tissues begin to sag, and wrinkles become more visible.
Les scientifiques ont démontré que la cause principale du vieillissement cutané était la diminution de la synthèse d’élastine.
By acting on the Extracellular Matrix (ECM), Kappa-Elastine helps combat the effects of skin aging.
Kappa-Elastine, a Powerful Anti-Aging Molecule
Thanks to its unique properties, Kappa-Elastine has the ability to help prevent skin aging by acting deep within the skin and rebuilding collagen and elastin networks.
Kappa-Elastine works through two complementary mechanisms:
- Its first action is immediate, thanks to its ability to rapidly restore the existing elastin network.
- Its second action is to stimulate collagen and elastin production, thereby promoting the reconstruction of the Extracellular Matrix (ECM).
IN VITRO TESTS (AFTER 6 HOURS)
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Increase in Type I Collagen.
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Increase in Type III Collagen.
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%
Increase in Elastin.
By targeting the mechanisms responsible for skin aging, Kappa-Elastine helps reduce wrinkles and prolong the skin’s youthful appearance.
Scientifically Proven Efficacy
Kappa-Elastine has been the subject of numerous scientific studies, including biochemical, histological, morphological, and toxicological research, conducted at leading university research centers.
IN VIVO TESTS
Increase in Skin Hydration Levels
Tested on all skin types and on patients of different ages, Kappa-Elastin has demonstrated significant results in improving skin hydration, elasticity, firmness, and reducing wrinkles.
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%
REDUCES EXPRESSION LINES
0
%
INCREASES HYDRATION*
0
%
INSTANTLY SMOOTHER SKIN
0
%
INCREASED FIRMNESS & TONE
The Power of Kappa-Elastine
Tests conducted by independent laboratories have confirmed excellent skin tolerance, with no allergic reactions or irritation observed. These studies have highlighted the various benefits of Kappa-Elastine:
Anti-wrinkle
Moisturising
Nourishing
Toning
Softening
Regenerating
Anti-sagging
Over 500 Scientific and Medical Publications on Kappa-Elastine
- Robert, L. (2009). The saga of κ-elastin or the promotion of elastin degradation products from “garbage” to receptor agonists and pharmacologically active principles. Connective Tissue Research.
- Hornebeck, W., Tixier, J. M., & Robert, L. (1986). Inducible adhesion of mesenchymal cells to elastic fibers: Elastonectin. Proceedings of the National Academy of Sciences, 83(15), 5517–5520.
- Brassart, B., Fuchs, P., Huet, E., Alix, A. J., Walach, J., Tamburro, A. M., Delacoux, F., Haye, B., Emonard, H., Hornebeck, W., & Debelle, L. (2001). Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts. Journal of Biological Chemistry, 276(7), 5222–5227.
- Robinet, A., Fahem, A., Cauchard, J. H., Huet, E., Vincent, L., Lorimier, S., Antonicelli, F., Soria, C., Crepin, M., Hornebeck, W., & Bellon, G. (2005). Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP. Journal of Cell Science, 118(2), 343–356.
- Robinet, A., Millart, H., Oszust, F., Hornebeck, W., & Bellon, G. (2007). Binding of elastin peptides to S-Gal protects the heart against ischemia/reperfusion injury by triggering the RISK pathway. The FASEB Journal, 21(9), 1968–1978.
KDerm: Anti-Aging Expertise
KDerm combines the powerful anti-aging properties of Kappa-Elastine bio-peptides with a rigorous dermocosmetic approach to offer a complete skincare range that brings together scientific excellence, efficacy, and respect for the skin.
Designed to help the skin combat the visible signs of aging, each product provides a targeted solution to its specific needs, delivering visible results from the very first days of use.
Scientifically proven efficacy, expertise recognized by dermatologists, and highly tolerable formulas suitable for all skin types.
With KDerm, the science of anti-aging becomes a natural part of everyday skincare.
Skincare Products Endorsed by Healthcare Professionals
Our KDerm skincare products are also listed in VIDAL, an essential reference for healthcare professionals in their medical and prescribing practices.
Used by 700,000 physicians across Europe, VIDAL relies on validated medical references and is updated daily by a team of healthcare experts, including physicians, pharmacists, and specialists in clinical and therapeutic pharmacology.
